Study timeline

4th August 2022 10:38

Status Update Archived

2022
31st January 2017 10:56

Status Update Completion

2017

External Policy impact added by Erwan Piriou

Together with few other studies forms part of the evidence package for WHO to recommend against the usage of so-called "tie-breaker" algorithms for HIV diagnosis, as this type of strategy causes false positive diagnoses.

2nd November 2016 10:54

Bilateral meeting dissemination added by Erwan Piriou

Share with MoH in country, with limited effect unfortunately on HIV testing policy. There are several reasons for this, including possibly limited resources allocated to advocacy on this topic, but more so a challenging situation whereby the medical/technical expert in country could be convinced, but do not have decision power regarding diagnostic choices, which are much more influenced by purely financial arguments (at the level of test purchasing).

2nd November 2016 10:52

Other impact added by Erwan Piriou

Used during several MSF-OCA annual laboratory workshop (as part of a larger set of evidence) to explain and illustrate the OCA strategy for HIV diagnosis.

2nd November 2016 10:50

MSF Policy impact added by Erwan Piriou

Adds evidence for the need of using appropriate HIV diagnostic algorithms, including preferably a confirmation test. This is very useful for internal purposes deciding on resource allocation.

2nd November 2016 10:48

Scientific meeting dissemination added by Erwan Piriou

Oral presentation on interim finding of the study, during an MSF symposium at the 2011 ICASA meeting in Addis Ababa, Ethiopia.

2nd November 2016 10:47

Scientific meeting dissemination added by Erwan Piriou

Oral presentation at the ASLM 2014 meeting in Cape Town (http://aslm2014.org/), on 01-Dec-2014, during a session on "HIV Diagnostics and Viral Load Testing".
Title of the presentation: "Time for Change? An Evaluation of the Tie-breaker Algorithm and the Role of Weakly Reactive Test Lines in Contributing to a High Rate of False Positive HIV Results"

Received great interest from WHO-PQ team as well as a.o. USAID people interested in pushing the issue of accurate HIV diagnoses.

2nd November 2016 10:46

Publication added by Erwan Piriou

Dilution testing using rapid diagnostic tests in a HIV diagnostic algorithm: a novel alternative for confirmation testing in resource limited settings Shanks, Leslie – Springer Nature (2015)
2nd November 2016 10:38

Publication added by Erwan Piriou

Accounting for False Positive HIV Tests: Is Visceral Leishmaniasis Responsible? Shanks, Leslie – Public Library of Science (PLoS) (2015)
2nd November 2016 10:37

Publication added by Erwan Piriou

Evaluation of HIV testing algorithms in Ethiopia: the role of the tie-breaker algorithm and weakly reacting test lines in contributing to a high rate of false positive HIV diagnoses Shanks, Leslie – Springer Nature (2015)
2nd November 2016 10:35
7th October 2016 18:03

Principal investigator changed by Kim West

Changed to “Erwan Piriou”

15th April 2016 10:36

Principal investigator changed by Kim West

Changed to “Kim West”

22nd March 2016 16:16

Status Update Implementation

24th February 2016 12:01

Status Update Concept

2016