TB- PRACTECAL: A randomised, controlled, open-label, phase II-III trial to evaluate the safety and efficacy of regimens containing bedaquiline and pretomanid for the treatment of adult patients with pulmonary multidrug resistant tuberculosis.

Principal investigator

Locations

Uzbekistan, Belarus
Topic

Tuberculosis
Methodology

Randomised controlled trial (RCT)
Reference

OCA015-02
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Purpose of study

Identify regimens containing bedaquiline and pretomanid for further evaluation based on safety and efficacy outcomes after 8 weeks of treatment. And to evaluate the safety and efficacy of the investigational regimens containing bedaquiline and pre...

Study status

Concept
Protocol & ERB
Implementation
Completion
Archived

Study timeline

Documents

132-protocol-2022-06-13.pdf 1.21 MB
132-publication-2024-09-24.pdf 1.25 MB

Publications

Principles for designing future regimens for multidrug-resistant tuberculosis

Brigden, Grania "–" WHO Press "(2013)"
Resistance to second-line drugs in multidrug-resistant tuberculosis

Nyang'wa, Bern-Thomas "–" Elsevier BV "(2013)"

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